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Study Status: 
Study Description: 

IRB Protocol #: 1701017892

Overview: To assess whether TAVR should be performed on patients who have been diagnosed with aortic stenosis, but have not yet developed symptoms. Patients who do not have symptoms will either undergo TAVR or be closely monitored with medical therapy.

Patients must:

  • Be older than 65
  • Have severe aortic stenosis
  • Have a negative treadmill stress test
  • Be informed of the nature of the study, agree to its provisions, and provide written informed consent as approved by the institutional review board of the clinical site 

Patients cannot participate if:

  • Symptomatic
  • Have any concomitant valvular, aortic, coronary artery disease requiring surgery making AVR a Class I indication
  • Have a pre-existing mechanical or bioprosthetic valve in any position
  • Have significant abdominal or thoracic aortic disease (such as aneurysm, severe calcification, aortic coarctation, etc.)

Early TAVR Trial: Evaluation of Transcatheter Aortic Valve Replacement Compared to SurveilLance for Patients with AsYmptomatic Severe Aortic Stenosis


Dr. S. Chiu Wong
Principle Investigator
Phone: (212) 746-4644

Dolores Reynolds, RN, BSN
Research Administrator
Phone: (212) 746-4617

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