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Study Name: ALIVE Study Objective: Determine the effect of GB002 on improving pulmonary hemodynamics in subjects with World Health Organization (WHO) Group 1 PAH who are WHO Functional Class (FC) II or III |
Key Inclusion Criteria:
b. PAH associated with one of the following connective tissue diseases (CTDs):
− Systemic sclerosis,
− Mixed CTD or overlap syndrome,
− Systemic lupus erythematosus.
c. PAH associated with anorexigen or methamphetamine use.
d. Congenital heart disease with simple systemic to pulmonary shunt at least 1 year
after surgical repair.
c. PVR ≥ 400 dyne•s/cm5.
Key Exclusion Criteria:
PI: Irina Sobol, MD (646) 962 5555
RC: Katelyn Bastert, (212) 746 2698